Showing posts with label Psoriasis Therapeutics. Show all posts
Showing posts with label Psoriasis Therapeutics. Show all posts

Tuesday, 5 February 2019

Psoriasis Therapeutics in Asia-Pacific Markets to 2024 - Increasing Prevalence, Advent of Novel Biologics and Pipeline Drugs to Drive the Market

Researchmoz added latest report "Psoriasis Therapeutics in Asia-Pacific Markets to 2024 - Increasing Prevalence, Advent of Novel Biologics and Pipeline Drugs to Drive the Market". The industry report lists the leading competitors and provides the insights strategic industry Analysis of the key factors influencing the market.
Psoriasis is a common, chronic inflammatory skin condition affecting around 2-3% of the world’s population. While the main cause of psoriasis remains uncertain, immunologic, genetic, and environmental factors appear to play a role. Common symptoms of psoriasis include inflammation, swelling, and patches of red, itchy, flaky skin called skin lesions.

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The most common sites of involvement are the scalp, elbows and knees, followed by nails, hands, feet and trunk. It is estimated that up to 30% of people with psoriasis eventually develop psoriatic arthritis. Psoriasis is a serious skin condition that has a significant negative impact on patients’ quality of life, interfering in many aspects of professional and social life.

Men and women are equally likely to get it, and the onset of psoriasis can occur at any age. However, the age of onset frequency proved to be bimodal - the first before 40 years of age and the second between 50 and 60 years of age. The extent and severity of the disease varies greatly between patients and often varies within individuals over the course of time.

There are different types of psoriasis, the most common being plaque psoriasis. Around 125 million people worldwide have psoriasis, of which 80% have plaque psoriasis. The current marketed drug landscape in psoriasis includes topical agents, systemic therapies (such as acitretin, cyclosporine and methotrexate) and biologic therapies. In recent years, the discovery of new immunological factors and better understanding of psoriasis have fundamentally changed the treatment of psoriasis and created new biological drugs against specific immunological elements that cause psoriasis.

Both IL-17 and IL-23 are promising targets in the treatment of moderate to severe plaque psoriasis. The biologic drugs targeting these cytokines and their receptors have proven to be effective and safe in clinical trials and have offered greater efficacy than pre-existing biologics, making them an attractive option for use prior to other biologics.

Therefore, during the forecast period, the dominance of TNF-? inhibitors (adalimumab, infliximab and etanercept) and interleukin (IL)-12/23 inhibitor ustekinumab will be challenged by the highly effective IL-17 and IL-23 inhibitor therapies. The late-stage psoriasis pipeline is composed of promising targeted therapies that have potential to achieve approval and launch during the forecast period.

These include Sun Pharma’s tildrakizumab, AbbVie’s risankizumab, Welichem Biotech’s Tapinarof, and UCB’s bimekizumab and certolizumab pegol. These new drugs will supplement current market leaders and offer broader therapeutic options.

Scope

- The Asia-Pacific psoriasis market will be valued at $1,997.3m in 2024, growing from $933.1m in 2017, at a compound annual growth rate (CAGR) of 11.5%.
- What are the key factors driving the Asia-Pacific psoriasis treatment market?
- How will novel IL-23 inhibitor therapy Tremfya, which holds first-to-market advantage, contribute to growth?
- What will be the impact of the new IL-17 and IL-23 inhibitor therapies?
- How will branded therapies be affected by upcoming pipeline therapies?
- The psoriasis pipeline contains a range of molecule types and molecular targets, including those that are well established in psoriasis and novel target therapies.
- Which molecular targets appear most frequently in the pipeline?
- Is there potential for pipeline molecules to address unmet needs within the psoriasis market?
- Late-stage pipeline therapies with a strong clinical record have the potential to enter the market over the forecast period.
- How have the late-stage therapies performed in clinical trials?
- Which classes of drugs are most prominent in the pipeline?
- How will the approval of risankizumab and tildrakizumab, which hold a key advantage in terms of dosing schedule over IL-23 competitor Tremfya, affect the competitive landscape?
- Various drivers and barriers will influence the market over the forecast period.
- What barriers will limit the uptake of premium-priced therapeutics in the assessed countries?
- What factors are most likely to drive the market in these countries?
- What licensing and co-development deals have occurred within this therapy area since 2007?

Get Complete TOC With Tables and Figures @ https://www.researchmoz.us/psoriasis-therapeutics-in-asiapacific-markets-to-2024-increasing-prevalence-advent-of-novel-biologics-and-pipeline-drugs-to-drive-the-market-report.html/toc

Reasons to buy

- Understand the current clinical and commercial landscape through a comprehensive analysis of disease symptoms, diagnostic methods, etiology, pathophysiology, epidemiology, prognosis and treatment.
- Visualize the composition of the psoriasis market in terms of dominant therapies, with their clinical and commercial standing. Unmet needs are highlighted to allow a competitive understanding of gaps in the market.
- Analyze the psoriasis pipeline and stratify pipeline therapies by stage of development, molecule type and molecular target.
- Understand the potential of late-stage therapies, with extensive profiles of products that could enter the market over the forecast period, highlighting clinical performance, potential commercial positioning, and how they will compete with other therapies.
- Predict psoriasis market growth in the five assessed Asia-Pacific markets, with epidemiological and annual cost of therapy forecasts across India, China, Australia, South Korea and Japan, as well as the individual contributions of promising late-stage molecules to market growth.
- Identify commercial opportunities in the psoriasis deals landscape by analyzing trends in licensing and co-development deals.

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Tuesday, 21 March 2017

Asia-Pacific Psoriasis Therapeutics Markets Advent of Novel Biologics 2021 | New Study

Researchmoz added Most up-to-date research on "Psoriasis Therapeutics in Asia-Pacific Markets to 2021: Advent of Novel Biologics and Expanding Treatment Pool to Drive Growth" to its huge collection of research reports.

GBI Research, the leading business intelligence provider, has released its latest research, ""Psoriasis Therapeutics in Asia-Pacific Markets to 2021: Advent of Novel Biologics and Expanding Treatment Pool to Drive Growth"", which provides insights into psoriasis therapeutics in the Asia-Pacific (APAC) market. For the purposes of this report, APAC refers to the market in China, India, Japan, and Australia only. The report estimates the market size for 2014, along with forecasts until 2021. It also covers disease epidemiology, treatment algorithms, treatment use patterns, in-depth analysis of pipeline molecules, clinical trial failure rates, and analysis of recent deals. It is built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis carried out by GBI Research’s team of industry experts.

To Get Sample Copy of Report visit @ http://www.researchmoz.us/enquiry.php?type=S&repid=285644

In 2014, the value of the psoriasis therapeutics market in APAC amounted to an estimated $690m, and it is forecast to grow at a Compound Annual Growth Rate (CAGR) of 8.4% between 2014 and 2021 to reach $1.2 billion. The psoriasis treatment landscape is a particularly complex one. More than 80% of patients fall into the mild-or-moderate category, for which the first line of treatment is topical drugs, phototherapy, or a combination. In the case of severe patients, non-steroidal drugs such as methotrexate, cyclosporine, and acitretin are practiced as first-line treatment; however, they come with toxicity concerns and so cannot be prescribed for long durations. Biologics such as TNF inhibitors (adalimumab, etanercept, infliximab) and ustekinumab are largely prescribed as second-line therapy when none of the aforementioned options provide the desired results. However, during the forecast period, biologics are likely gain a significant patient share due to healthcare plans in APAC and awareness regarding the effectiveness of biologics. Among the recently launched biologics, Cosentyx (secukinumab) from Novartis has shown better efficacy than Enbrel (etanercept), and is a novel molecule that targets Interluekin-17 (IL-7). Biocon India has launched Alzumab (itolizumab), which is a first-in-class novel molecule that targets CD6 protein. It is anticipated to be the leading biologic in India by the end of forecast period. Humira (adalimumab), Enbrel (etanercept), and Remicade (infliximab) are expected to lose their patent during the forecast period, but will be compensated for by biosimilar versions.

Scope

- The report analyzes treatment use patterns, market characterization, the pipeline, and key licensing and co-development deals for psoriasis in the APAC markets of China, India, Japan, and Australia.The report includes
- A brief introduction to psoriasis, including pathophysiology, etiology, diagnosis, and treatment algorithms
- In-depth analysis of currently marketed drugs, including analysis of safety, efficacy, treatment patterns, and strengths/weaknesses, along with a heat map comparing them in terms of safety and efficacy
- A comprehensive review of the pipeline for psoriasis, including individual analysis of a number of late-stage pipeline drugs likely to enter the market during the forecast period; the pipeline is further analyzed on the basis of phase distribution, molecule type, program type, mechanism of action, and molecular target
- Additional in-depth analysis of pipeline drug clinical trials by phase, trial size, trial duration, and program failure rate for each molecule type
- Multi-scenario forecast data for the market to 2021, taking into account how it might be affected by the introduction of new drugs, the expiry of key patents on current drugs, and changes in disease epidemiology across the key developed markets
- Discussion of the drivers of and barriers to market growth
- In-depth analysis of all licensing and co-development deals that have occurred in the psoriasis market since 2006

Reasons to buy

The report will enhance your decision-making capability by allowing you to

- Understand the psoriasis pipeline and the factors that indicate that it is becoming more innovative
- Analyze detailed profiles for promising pipeline products and gain insights into how they are likely to compete in the market and who their main competitors will be
- Follow the trends in psoriasis clinical trial size and duration in relation to industry averages
- Assess the potential risk of future developmental programs for psoriasis therapeutics by mechanism of action using recorded clinical trial failure rates
- Analyze the potential growth patterns expected for the psoriasis market over the forecast period
- Identify the countries that are expected to contribute the most to this growth and devise a more effectively tailored country strategy through an understanding of key drivers and barriers
- Accelerate and strengthen your market position by identifying key companies for strategic partnerships

Make an Enquiry of this report @ http://www.researchmoz.us/enquiry.php?type=E&repid=285644

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