Wednesday, 20 March 2019

Current Research & Developments Status of Chimeric Antigen Receptor (CAR) T-Cell Therapy

Recently, a fresh study highlighting the market snapshot of "Current Research & Developments Status of Chimeric Antigen Receptor (CAR) T-Cell Therapy" has been publicized to the wide database of Researchmoz.
CAR T-Cell Design and Evolution
Chimeric antigen receptors (CARs, also known as chimeric immunoreceptors, chimeric T-cell receptors, artificial T-cell receptors or CAR-T) are engineered receptors that graft an arbitrary specificity onto an immune effector cell (T-cell). Typically, these receptors are used to graft the specificity of a monoclonal antibody onto a T-cell, with transfer of their coding sequence facilitated by retroviral vectors. The receptors are called chimeric because they are composed of parts from different sources.
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FDA Product Approvals
There are two chimeric antigen receptor T-cell (CAR T) therapies currently approved by the U.S. FDA.
1. On Aug. 30, 2017, Novartis announced that the U.S. FDA had approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T-cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.
2. On Oct. 18, 2017, the U.S. FDA approved Yescarta (axicabtagene ciloleucel) (Kite Pharma Inc.), a cell-based gene therapy, for the treatment of adult patients with relapsed or refractory large Bcell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, primary mediastinal large B-cell lymphoma, highgrade B-cell lymphoma and DLBCL arising from follicular lymphoma. Yescarta is not indicated for
the treatment of patients with primary central nervous system lymphoma. It is a CD19-directed genetically modified autologous T-cell immunotherapy.
Market Analysis
It has been estimated that the global market for CAR T-cell therapies, as defined in the reports market segmentation, was valued at $REDACTED million in 2017 and $REDACTED million in 2018. By the end of the forecast period in 2023, it is predicted that the global market will have increased in value to $REDACTED billion,representing a compound annual growth rate (CAGR) of REDACTED%.
Analysis of the global CAR T-cell therapy market shows that North America is by far the largest geographic region in terms of revenue with an estimated REDACTED% global share. The European market is the second largest regional market with an estimated REDACTED% global share and Asia-Pacific has a very small REDACTED% share of the global market in 2018."
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Report Scope
The key objectives of this study are to:
- Review the historical development of CAR T-cell technology.
- Discuss the principles of chimeric antigen receptor design.
- Understand the mechanisms of action associated with CAR T-cell immunotherapy.
- Highlight the ongoing clinical and non-clinical advancements in the field of CAR T-cell therapy.
- Access the side effects, disadvantages and limitations of existing CAR T-cell technologies.
- Examine the current marketed drugs, including development activities and details of patent expirations.
- Determine the production methods for CAR T-cells.
- Review the range of joint ventures, collaborations, license and research agreements currently focused on CAR T-cell technology.
- Review of the regulatory requirements.
- Review the global CAR T-cell therapy market dynamics.
- Survey the key players involved in the development of therapeutics for CAR T-cell immunotherapy and provide company profiles.
By purchasing this study, the reader will gain:
- An improved understanding of the current state and future of this exciting, new and innovative technology.
- The latest information on the leading companies engaged in developing this technology, clinical trials being conducted, a review of the status of their intellectual property, product pipelines and insight into their proprietary technologies.
- The role and influence of individual countries relating to the development of CAR T-cell therapy and the number of CAR T-cell trials in the U.S. versus China and other countries.
- Knowledge of the market potential for the CAR T-cell therapy market and anticipated development of the market.
- The analysis includes the use of charts and graphs measuring product growth and trends within the marketplace. In addition, an analysis of the incidence and mortality associated with cancers and the target market helps provide the reader with a deeper understanding of the possibilities for future treatment and avenues for possible R&D budgets. Company-specific information, including sales figures, product pipeline status and R&D trends, is provided throughout the report.
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Report Includes
- 31 data tables and 41 additional tables
- An overview of global market for current research & developments status of Chimeric Antigen Receptor (CAR) T-cell therapy
- Analyses of global market trends, with data from 2017, estimates for 2018, and projections of compound annual growth rates (CAGRs) through 2023
- Understand market dynamics of CAR T-Cell therapy, along with the growth driving factors, restraints and future scope
- Information on competitor initiatives, research and development status of CAR T-cell therapy
- Comprehensive company profiles of major players in the market including, Amgen, Avacta Life Sciences Ltd., Bluebird Bio Inc., Novartis Ag, Servier Laboratories, Takeda Pharmaceuticals, and Transgene SA
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Global Ethylene Acrylic Acid Adhesive Market to Undertake Strapping Growth by the End 2023

Researchmoz offers a latest published report on “Global Ethylene Acrylic Acid Adhesive Market 2018 by Manufacturers, Regions, Type and Application, Forecast to 2023” delivering key insights and providing a competitive advantage to clients through a detailed report.
Ethylene acrylic acid adhesive is the copolymer of ethylene and acrylic acid. Ethylene Acrylic Acid (EAA) copolymers provide a unique combination of properties that take advantage of respective comonomers (E and AA), used in their preparation. The presence of AA reduces the crystallinity of E segments. Increasing the AA content in a copolymer, will not only result in a more amorphous molecule, but will also significantly improve the adhesion performance.
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Scope of the Report:
This report focuses on the Ethylene Acrylic Acid Adhesive in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
The report provides a basic overview of the Ethylene Acrylic Acid Adhesive industry including definitions, classifications, applications and industry chain structure.
Then, the report focuses on global major leading industry players with information such as company profiles, product picture and specifications, sales, market share and contact information. Whats more, the Ethylene Acrylic Acid Adhesive industry development trends and marketing channels are analyzed.
The worldwide market for Ethylene Acrylic Acid Adhesive is expected to grow at a CAGR of roughly 1.9% over the next five years, will reach 1500 million US$ in 2023, from 1360 million US$ in 2017, according to a new GIR (Global Info Research) study.
Market Segment by Manufacturers, this report covers
DowDuPont
ExxonMobil Chemical
Honeywell
LyondellBasell
Michelman
BYK
Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
FilmGrade
ExtrusionCoatingGrade
DispersibleGrade
Market Segment by Applications, can be divided into
Packaging Applications
Industrial Applications
Other
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There are 15 Chapters to deeply display the global Ethylene Acrylic Acid Adhesive market.
Chapter 1, to describe Ethylene Acrylic Acid Adhesive Introduction, product scope, market overview, market opportunities, market risk, market driving force;
Chapter 2, to analyze the top manufacturers of Ethylene Acrylic Acid Adhesive, with sales, revenue, and price of Ethylene Acrylic Acid Adhesive, in 2016 and 2017;
Chapter 3, to display the competitive situation among the top manufacturers, with sales, revenue and market share in 2016 and 2017;
Chapter 4, to show the global market by regions, with sales, revenue and market share of Ethylene Acrylic Acid Adhesive, for each region, from 2013 to 2018;
Chapter 5, 6, 7, 8 and 9, to analyze the market by countries, by type, by application and by manufacturers, with sales, revenue and market share by key countries in these regions;
Chapter 10 and 11, to show the market by type and application, with sales market share and growth rate by type, application, from 2013 to 2018;
Chapter 12, Ethylene Acrylic Acid Adhesive market forecast, by regions, type and application, with sales and revenue, from 2018 to 2023;
Chapter 13, 14 and 15, to describe Ethylene Acrylic Acid Adhesive sales channel, distributors, traders, dealers, Research Findings and Conclusion, appendix and data source
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Global Miniature Ball Bearings Market to Perceive Substantial Growth by the End 2023

"Global Miniature Ball Bearings Market 2018 by Manufacturers, Regions, Type and Application, Forecast to 2023" report provides the newest industry data and industry future trends, allowing you to identify the products and end users driving Revenue growth and profitability.
Ball Bearings is a bearing consisting of a number of hard steel balls rolling between a metal sleeve fitted over the rotating shaft and an outer sleeve held in the bearing housing, so reducing friction between moving parts while providing support for the shaft.
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Scope of the Report:
This report focuses on the Miniature Ball Bearings in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
At present, in the foreign developed countries the miniature ball bearings industry on a higher level than other countries, the world's large enterprises are mainly concentrated in Japan. Meanwhile, foreign companies have variety products, strong R & D capability, the technical level is in a leading position.
Although sales of miniature ball bearings brought a lot of opportunities, the study group recommends the new entrants just having money but without technical advantage and downstream support do not enter into the miniature ball bearings field.
The worldwide market for Miniature Ball Bearings is expected to grow at a CAGR of roughly 4.2% over the next five years, will reach 2380 million US$ in 2023, from 1860 million US$ in 2017, according to a new GIR (Global Info Research) study.
Market Segment by Manufacturers, this report covers
Minebea Group,
NSK,
SKF,
Kitanihon Seiki,
FAG(Barden),
Timken,
NTN,
GRW Bearings,
Pacamor Kubar,
Shanghai TianAn,
HUANCHI,
HONGSHAN,
SWC Bearings,
CW Bearings,
Shanghai HengAn,
Shanghai LieLi
Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
Open miniature ball bearings
Dust over miniature ball bearings
Market Segment by Applications, can be divided into
Dental
X-ray
Fuel Controls
Flow-meters
Spindle bearings / dressing spindles
Instrument
Turbo molecular pumps
Automotive
Others
Get Complete TOC With Tables and Figures @ https://www.researchmoz.us/global-miniature-ball-bearings-market-2018-by-manufacturers-regions-type-and-application-forecast-to-2023-report.html/toc
There are 15 Chapters to deeply display the global Miniature Ball Bearings market.
Chapter 1, to describe Miniature Ball Bearings Introduction, product scope, market overview, market opportunities, market risk, market driving force;
Chapter 2, to analyze the top manufacturers of Miniature Ball Bearings, with sales, revenue, and price of Miniature Ball Bearings, in 2016 and 2017;
Chapter 3, to display the competitive situation among the top manufacturers, with sales, revenue and market share in 2016 and 2017;
Chapter 4, to show the global market by regions, with sales, revenue and market share of Miniature Ball Bearings, for each region, from 2013 to 2018;
Chapter 5, 6, 7, 8 and 9, to analyze the market by countries, by type, by application and by manufacturers, with sales, revenue and market share by key countries in these regions;
Chapter 10 and 11, to show the market by type and application, with sales market share and growth rate by type, application, from 2013 to 2018;
Chapter 12, Miniature Ball Bearings market forecast, by regions, type and application, with sales and revenue, from 2018 to 2023;
Chapter 13, 14 and 15, to describe Miniature Ball Bearings sales channel, distributors, traders, dealers, Research Findings and Conclusion, appendix and data source
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ResearchMoz is the one stop online destination to find and buy market research reports & Industry Analysis. We fulfil all your research needs spanning across industry verticals with our huge collection of market research reports. We provide our services to all sizes of organisations and across all industry verticals and markets. Our Research Coordinators have in-depth knowledge of reports as well as publishers and will assist you in making an informed decision by giving you unbiased and deep insights on which reports will satisfy your needs at the best price.
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Global Electrical Insulation Materials Market to Observe Strong Development by 2023

ResearchMoz presents detailed study of "Global Electrical Insulation Materials Market 2018 by Manufacturers, Regions, Type and Application, Forecast to 2023". The report also identifies and analyses the emerging trends along with major drivers, challenges and opportunities in the Track and Trace Solutions Market.
The main aim of Electrical Insulation Materials is to separate electrical conductors without passing current from one to the other and to safeguard individuals from electrically energized wires and parts. A complete knowledge of Electrical Insulation Materials and standards for safe working practices is required.
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Scope of the Report:
This report focuses on the Electrical Insulation Materials in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
The industry is expected to remain innovation-led, with frequent acquisitions and strategic alliances adopted as the key strategies by the players to increase their industry presence. Meanwhile, optimize product mix and further develop value-added capabilities to maximize margins.
The Electricity Power application dominated the Electrical Insulation Materials market during the forecast period, closely followed by Electrical and Electronics industry in 2016. New Energy industry application is also expected to witness high growth rate between 2016 and 2022.
Currently, China is the largest Electrical Insulation Materials market, in terms of value, closely followed by Europe. Some of the factors driving the growth of the North American market are high growth of end-use industries, local manufacturing, and increased number of domestic players in various market segments.
The worldwide market for Electrical Insulation Materials is expected to grow at a CAGR of roughly 5.2% over the next five years, will reach 13700 million US$ in 2023, from 10100 million US$ in 2017, according to a new GIR (Global Info Research) study.
Market Segment by Manufacturers, this report covers
Weidmann (WICOR Group)
Dupont
Krempel
Pucaro (ABB)
Elantas Electrical Insulation
3M
Von Roll
Toray
ISOVOLTA AG
Nitto Denko Corporation
Sichuan EM Technology
Axalta (The Carlyle Group)
Suzhou Jufeng
Suzhou Taihu
Zhejiang Rongtai
Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
Electrical Insulating Resins & Coatings
Electrical Laminates and Moulded Products
Film and Composite Materials
Mica Products
Prepregs and Impregnating Insulation Materials
Electrical Plastics
Others
Market Segment by Applications, can be divided into
Electricity Power
Electrical and Electronics
Motor
Aerospace
New Energy
Others
Get Complete TOC With Tables and Figures @ https://www.researchmoz.us/global-electrical-insulation-materials-market-2018-by-manufacturers-regions-type-and-application-forecast-to-2023-report.html/toc
There are 15 Chapters to deeply display the global Electrical Insulation Materials market.
Chapter 1, to describe Electrical Insulation Materials Introduction, product scope, market overview, market opportunities, market risk, market driving force;
Chapter 2, to analyze the top manufacturers of Electrical Insulation Materials, with sales, revenue, and price of Electrical Insulation Materials, in 2016 and 2017;
Chapter 3, to display the competitive situation among the top manufacturers, with sales, revenue and market share in 2016 and 2017;
Chapter 4, to show the global market by regions, with sales, revenue and market share of Electrical Insulation Materials, for each region, from 2013 to 2018;
Chapter 5, 6, 7, 8 and 9, to analyze the market by countries, by type, by application and by manufacturers, with sales, revenue and market share by key countries in these regions;
Chapter 10 and 11, to show the market by type and application, with sales market share and growth rate by type, application, from 2013 to 2018;
Chapter 12, Electrical Insulation Materials market forecast, by regions, type and application, with sales and revenue, from 2018 to 2023;
Chapter 13, 14 and 15, to describe Electrical Insulation Materials sales channel, distributors, traders, dealers, Research Findings and Conclusion, appendix and data source
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Global Prestressed Concrete Cylinder Pipe Market to Flourish with an Impressive CAGR by 2025

ResearchMoz presents professional and in-depth study of "Global Prestressed Concrete Cylinder Pipe Market Research Report 2019". This research assessment offers a clear insight about the influential factors that are expected to transform the global market in the near future.
Prestressed concrete cylinder pipe (PCCP) consists of a concrete core, a thin steel cylinder, high tensile prestressing wires, and a mortar coating. Concretes high compressive strength and steels high tensile strength forms a durable structure that can stand extreme condition. The thick mortar coating on the pipe protects the steel cylinder, joint rings, and pre-stressing wire from corrosion, which makes it ideal for water transmission, municipal wastewater applications, and industrial piping. PCCP does not require any bracing, compacted bedding, trucking in aggregate, unshrinkable fill, and welding, which makes it easier and economical to install.
The global Prestressed Concrete Cylinder Pipe market is valued at xx million US$ in 2018 is expected to reach xx million US$ by the end of 2025, growing at a CAGR of xx% during 2019-2025.
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This report focuses on Prestressed Concrete Cylinder Pipe volume and value at global level, regional level and company level. From a global perspective, this report represents overall Prestressed Concrete Cylinder Pipe market size by analyzing historical data and future prospect. Regionally, this report focuses on several key regions: North America, Europe, China and Japan.
At company level, this report focuses on the production capacity, ex-factory price, revenue and market share for each manufacturer covered in this report.
The following manufacturers are covered:
Pure Technologies Ltd.
Ameron International Corporation
Csawwa
WaterRF
Hume Pipe
Phoenix
Zhejiang Dragon Pipe
Xinjiang Guotong Pipeline
Shandong Longquan Pipeline Engineering
Ningxia Qinglong Pipes Industry
Segment by Regions
North America
Europe
China
Japan
Segment by Type
Embedded Steel Cylinder/Embedded Cylinder Pipe (ECP)
Outer Steel Cylinder/Lined Cylinder Pipe (LCP)
Segment by Application
Water Transmission & Distribution
Cooling Water System
Sewer Force Mains
Subaqueous Pipelines
Others
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ResearchMoz is the one stop online destination to find and buy market research reports & Industry Analysis. We fulfil all your research needs spanning across industry verticals with our huge collection of market research reports. We provide our services to all sizes of organisations and across all industry verticals and markets. Our Research Coordinators have in-depth knowledge of reports as well as publishers and will assist you in making an informed decision by giving you unbiased and deep insights on which reports will satisfy your needs at the best price.
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Global Sterilization Technologies Market will Observe Lucrative Surge by the End 2025

Researchmoz added latest report "Global Sterilization Technologies Market Research Report 2019". The industry report lists the leading competitors and provides the insights strategic industry Analysis of the key factors influencing the market.
This report analyzed the sterilizationequipment. Sterilizationequipment is used for sterilization and disinfecting, widely used in health care, pharmaceuticals, food-production facilities, etc.
The global Sterilization Technologies market is valued at xx million US$ in 2018 is expected to reach xx million US$ by the end of 2025, growing at a CAGR of xx% during 2019-2025.
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This report focuses on Sterilization Technologies volume and value at global level, regional level and company level. From a global perspective, this report represents overall Sterilization Technologies market size by analyzing historical data and future prospect. Regionally, this report focuses on several key regions: North America, Europe, China and Japan.
At company level, this report focuses on the production capacity, ex-factory price, revenue and market share for each manufacturer covered in this report.
The following manufacturers are covered:
Steris Corporation
GETINGE AB
Tuttnauer
BELIMED
Advanced Sterilization Products
Yamato
3M
Matachana group
MMM group
SAKURA
Systec
Telstar
SHINVA
LOAKEN
Runyes
Senoh Medical Equipment
Shenan Medical Instrument
Segment by Regions
North America
Europe
China
Japan
Segment by Type
Heat Sterilization
Low Temperature Sterilization
Others
Segment by Application
Pharmaceutical Industry
Hospitals
Others
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ResearchMoz is the one stop online destination to find and buy market research reports & Industry Analysis. We fulfil all your research needs spanning across industry verticals with our huge collection of market research reports. We provide our services to all sizes of organisations and across all industry verticals and markets. Our Research Coordinators have in-depth knowledge of reports as well as publishers and will assist you in making an informed decision by giving you unbiased and deep insights on which reports will satisfy your needs at the best price.
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Global Ultrasound Devices Market will Observe Lucrative Surge by the End 2025

Researchmoz added Most up-to-date research on "Global Ultrasound Devices Market Research Report 2019" to its huge collection of research reports. An insight on the important factors and trends influencing the market.
This report analzyed the ultrasound devices that are applied as special medical device used in ultrasonography for diagnostic purpose. Ultrasonography, commonly known as ultrasound, is a popular medical imaging technique used in diagnostics, and which uses high-frequency sound pulses and their echoes to specific body regions. Ultrasonic waves are specifically helpful in visualizing or imaging subcutaneous or internal body structures including muscles, tendons, vessels, joints or internal organs for any pathology or lesions.
The global Ultrasound Devices market is valued at xx million US$ in 2018 is expected to reach xx million US$ by the end of 2025, growing at a CAGR of xx% during 2019-2025.
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This report focuses on Ultrasound Devices volume and value at global level, regional level and company level. From a global perspective, this report represents overall Ultrasound Devices market size by analyzing historical data and future prospect. Regionally, this report focuses on several key regions: North America, Europe, China and Japan.
At company level, this report focuses on the production capacity, ex-factory price, revenue and market share for each manufacturer covered in this report.
The following manufacturers are covered:
General Electric (GE)
Philips
Siemens
TOSHIBA
Hitachi Medical
Mindray
Sonosite (FUJIFILM )
Esaote
Samsung Medison
Konica Minolta
SonoScape
LANDWIND MEDICAL
SIUI
CHISON
EDAN Instruments
Segment by Regions
North America
Europe
China
Japan
Segment by Type
2D
3D&4D
Doppler
Segment by Application
Radiology/Oncology
Cardiology
Obstetrics & Gynecology
Mammography/Breast
Emergency Medicine
Vascular
Others
Get Complete TOC With Tables and Figures @ https://www.researchmoz.us/global-ultrasound-devices-market-research-report-2019-report.html/toc
About ResearchMoz
ResearchMoz is the one stop online destination to find and buy market research reports & Industry Analysis. We fulfil all your research needs spanning across industry verticals with our huge collection of market research reports. We provide our services to all sizes of organisations and across all industry verticals and markets. Our Research Coordinators have in-depth knowledge of reports as well as publishers and will assist you in making an informed decision by giving you unbiased and deep insights on which reports will satisfy your needs at the best price.
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Current Research & Developments Status of Chimeric Antigen Receptor (CAR) T-Cell Therapy

Recently, a fresh study highlighting the market snapshot of "Current Research & Developments Status of Chimeric Antigen Receptor (...